Association of Interferon-Gamma Gene Polymorphism (+874 T/A) with Systemic Sclerosis
نویسندگان
چکیده
منابع مشابه
Association of Interferon-Gamma Gene Polymorphism (+874 T/A) with Systemic Sclerosis
Isabela J. Wastowskia,c,∗, Percival D. Sampaio-Barrosb,d, Gustavo Martelli-Palominoa, João Francisco Marques-Neto b, Janaina C.O. Crispim a, Diane M. Rassi a and Eduardo A. Donadi a Program of Basic and Applied Immunology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil Unit of Rheumatology, Department of Internal Medicine, Faculty of Medical Sciences, State University of...
متن کاملinterferon-gamma gene polymorphism in iranian patients with multiple sclerosis
interferon- gamma (ifn- γ) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (ms). a single nucleotide polymorphism, t to a, at position +874 in the first intron has previously been shown. this polymorphism is associated with ifn- γ production level. to study the effect of this polymorphism on susceptibility to multiple scle...
متن کاملInterferon-Gamma Gene Polymorphism in Patients with Tuberculosis
Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 hea...
متن کاملInterferon-gamma gene polymorphism in Iranian patients with multiple sclerosis.
Interferon- gamma (IFN- gamma) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (MS). A single nucleotide polymorphism, T to A, at position +874 in the first intron has previously been shown. This polymorphism is associated with IFN- gamma production level. To study the effect of this polymorphism on susceptibility to multi...
متن کاملThe interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome
BACKGROUND Cytokines play important roles in antiviral action. We examined whether polymorphisms of IFN-gamma,TNF-alpha and IL-10 affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS). METHODS A case-control study was carried out in 476 Chinese SARS patients and 449 healthy controls. We tested the polymorphisms of IFN-gamma,TNF-alpha and IL-10 for their associat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Disease Markers
سال: 2009
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2009/936152